| Date | Location | Result | |
| 02/27/10 | Babson Park, MA | WPI 56, Wellesley 46 | Box score |
| 02/24/10 | Springfield, MA | Wellesley 58, Springfield College 57 | Box score |
| 02/20/10 | Wellesley, MA | Springfield College 77, Wellesley 61 | Box score |
| 02/17/10 | Norton, MA | Wheaton College 67, Wellesley 48 | Box score |
| 02/13/10 | Wellesley, MA | WPI 45, Wellesley 41 | Box score |
| 02/11/10 | Babson Park, MA | Babson College 71, Wellesley 44 | Box score |
| 02/06/10 | Cambridge, MA | Wellesley 60, MIT 51 | Box score |
| 02/03/10 | Wellesley, MA | Wellesley 67, Coast Guard 52 | Box score |
| 01/30/10 | Wellesley, MA | Wellesley 55, Mount Holyoke College 42 | Box score |
| 01/27/10 | Wellesley, MA | Wellesley 78, Clark 59 | Box score |
| 01/23/10 | Northampton, MA | Smith College 66, Wellesley 61 | Box score |
| 01/20/10 | Wellesley, MA | Wellesley 61, Wheaton College 59 | Box score |
| 01/16/10 | Worcester, MA | WPI 71, Wellesley 52 | Box score |
| 01/13/10 | Wellesley, MA | Babson College 72, Wellesley 46 | Box score |
| 01/09/10 | Springfield, MA | Springfield College 63, Wellesley 53 | Box score |
| 01/06/10 | Wellesley, MA | Smith College 55, Wellesley 42 | Box score |
| 12/11/09 | Wellesley, MA | Wellesley 75, MIT 47 | Box score |
| 12/09/09 | New London, CT | Coast Guard 47, Wellesley 44 | Box score |
| 12/05/09 | South Hadley, MA | Mount Holyoke College 61, Wellesley 57 | Box score |
| 12/02/09 | Worcester, MA | Clark 71, Wellesley 45 | Box score |
| 11/30/09 | Wellesley, MA | Wellesley 55, Wentworth 39 | Box score |
| 11/24/09 | Wellesley, MA | Brandeis University 64, Wellesley 52 | Box score |
| 11/21/09 | Wellesley, MA | Wellesley 58, Albertus Magnus 35 | Box score |
| 11/19/09 | Wellesley, MA | Roger Williams 39, Wellesley 33 | Box score |
| 11/17/09 | Providence, RI | Rhode Island College 72, Wellesley 53 | Box score |